First New Antibiotic in 60 Years, Thanks to AI

Artificial Intelligence (AI) has aided in the discovery of a new antibiotic targeting the drug-resistant Staphylococcus aureus, commonly known as MRSA. This breakthrough is crucial given MRSA’s status as a superbug, notorious for its resilience against conventional treatments, leading to over 35,000 deaths annually.

Utilizing a deep-learning algorithm, scientists identified novel compounds and assessed their efficacy against MRSA. James Collins, a professor at MIT and one of the study’s authors, highlighted the AI’s ability to predict potential antibiotics. However, conventional AI models often operate as ‘Black Box’ systems, lacking transparency in their decision-making process.

To address this limitation, researchers adapted an algorithm called Monte Carlo tree search, previously used in explainable AI systems like AlphaGo. This modification enabled the AI model to not only estimate antimicrobial activity but also provide insights into the molecular structures responsible for this activity.

The findings have been shared with Phare Bio, a nonprofit associated with the Antibiotics-AI Project, for further analysis of the compounds’ properties and potential clinical applications. Meanwhile, Collins’ lab continues to design new drug candidates based on these insights and employs AI models to explore solutions for combating other bacterial strains.

It is great to see the good side of advancing technologies!

Killing 10,000 Trees to Save the Forest

Sometimes the right thing for the environment looks like the wrong thing.

When most people thing of reforestation, they think of planting trees, but sometimes the best thing to do is to tear them down.

In Scotland, the old growth forests have been decimated and much of the countries biodiversity with it. However, a growing initiative is turning it around. And they are doing it by tearing things up… literally.

Check out this YouTube video showing how they are revitalizing the forest of this beautiful country!

Hunt for Most Valuable British Shipwreck

A team of marine experts aims to locate a historically significant shipwreck that sank 400 years ago, carrying an estimated $4.3 billion worth of gold.

The Royal Merchant, a 17th-century English treasure ship, sank in 1641 off Lands End, eastern England, during bad weather. Laden with riches from Mexico, including approximately 100,000 pounds of gold, 400 bars of Mexican silver, and 500,000 silver Pesos, the vessel carried a crew of 80 under the command of Captain John Limbrey. Its hold was reported to contain a substantial fortune in silver, gold, and jewels.

In recent times, speculation arose when a substantial anchor, potentially belonging to the Royal Merchant, was retrieved off the coast of Cornwall by The Spirited Lady in 2019. Now, a team of marine cargo recovery experts from Cornish-based company Multibeam Services, aided by former local fishermen, is gearing up to search for the wreck and its treasure.

Multibeam Services, equipped with advanced technology, plans an extensive search throughout 2024, covering a 200-square-mile area of the English Channel. Utilizing remote-controlled unmanned submersibles fitted with sonar and cameras, each valued at approximately $3.8 million, the team is confident in their ability to locate the wreckage.

Previous reports suggested the wrecks discovery by Odyssey Marine Exploration, legal disputes ensued, with the wreck purportedly being identified as a Spanish frigate, according to State Department Cables from Wikileaks.

It will be fascinating to see if they can find it and even more, who the treasure will belong to, once it is found.

Finland Remains Happiest Country for 7th Year

Finland consistently secures the top spot as the happiest country in the world, as per the annual United Nations World Happiness Report, a position it has maintained since 2018.

The Finnish people attribute their happiness to four fundamental factors: a strong bond with nature, a pragmatic lifestyle, emphasis on fresh and local food, and a commitment to sustainability.

They view happiness not as an enigmatic concept but rather as a set of attainable skills, cultivated through daily activities such as forest walks, sea dips post-sauna, and meals crafted from locally sourced ingredients.
To commemorate their happiness status and following the success of the 2023 Masterclass in Happiness, Finland’s official tourism board and Helsinki Partners are inviting applicants worldwide to participate in a happiness hack-a-thon. This five-day curated experience will take place in Helsinki, the world’s happiest capital.

Scheduled for June 2024, the Helsinki Happiness Hacks urban expedition offers selected participants an opportunity to learn from five Helsinki residents, each sharing their strategies for finding joy in the city.

The lineup includes Lena Salmi, a seventy-year-old skateboarder and avid swimmer, who will share insights on urban swimming; Luka Balac, a renowned chef focused on sustainability, who will discuss his approach to social gastronomy; Adela Pajunen, a well-being expert and biologist, who will shed light on Finland’s natural remedies; designer Tero Kuitunen, who will demonstrate how Helsinki’s urban and natural elements intersect; and Tapio Hakanen, also known as DJ Orkidea, who will introduce participants to the concept of a “sauna rave.”

Heli Jimenez, Senior Director of International Marketing at Business Finland, expresses enthusiasm about sharing Finnish happiness practices with the world. She states, “As the world’s happiest country, we believe in sharing our happiness. We are excited to welcome people from across the globe to discover the keys and hacks to Finnish happiness.”