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A new device, called the Diadem, has shown promising results in relieving pain and depression during clinical trials. It uses sound waves to target specific areas of the brain with millimeter accuracy. While non-drug treatments like this can raise skepticism, especially given the widespread use of SSRIs for depression, the research team is enthusiastic.

Lead author Tom Riis, a postdoctoral researcher at the University of Utah’s Department of Biomedical Engineering, reports significant improvements in patients after just one 40-minute session.

“Not every participant saw drastic changes, but for those who did, the results were remarkable,” said Riis. “In some cases, you could see the difference immediately—their mood and behavior had completely shifted.”

The device is in phase 2 trials, and the team is eager to move forward. Of 20 participants, 60% reported a 33% reduction in pain right after treatment. For those with depression, 10 of 14 reported remission a week later after just one session.

The Diadem sends ultrasonic frequencies to areas of the brain involved in pain and emotion regulation, like the anterior cingulate cortex. The device’s precision allows it to reach the target areas through the skull.

One patient described the experience as their brain “waking up,” while another reported feeling unusually clear-headed while walking through a grocery store. The team is now recruiting participants for phase 3 trials and can be contacted at diademclinicaltrials@gmail.com.

Just off the coast of Tela, Honduras, a coral reef has caught the attention of the marine science community. This reef defies what we know about coral survival. Despite threats like warm waters, boat traffic, agricultural runoff, and murky water, the Tela Bay reef isn’t just surviving—it’s thriving. Live coral cover here is around 65%, compared to the Caribbean average of just 18%.

Scientists are trying to understand what makes the Tela Reef so resilient and whether its secrets can help save other threatened reefs in the Gulf of Mexico. Research by National Geographic and the University of Miami highlights the presence of elkhorn coral—a critically endangered species—flourishing in Tela under conditions that have devastated it elsewhere, like in the Florida Keys.

Andrew Baker, a marine scientist from the University of Miami, explained that Florida’s elkhorn populations are struggling with rising temperatures. He suggests that introducing genetic diversity from resilient populations like Tela’s might help.

Various theories have been proposed to explain Tela’s resilience. One suggests that periodic influxes of saline water from the Gulf kill harmful bacteria and algae. Another theory is that the reef’s richness makes it less attractive to fishermen, leaving the coral undisturbed. A more promising idea is that the coral in Tela hosts heat-resistant symbionts—microorganisms that live inside coral cells and provide energy through photosynthesis. These symbionts may help the coral cope with warmer, more acidic water.

In addition to the unique coral, Tela Bay also has a population of long-spined sea urchins, which were nearly wiped out in the 1980s. These urchins graze on algae that could otherwise overwhelm the coral.

Scientists are not waiting for a definitive answer. They’ve established a coral breeding center in Tela, aiming to spread the genetic traits of Tela coral to reefs worldwide. The University of Miami’s Coral Reef Futures Lab and the Florida Aquarium in Tampa are already cross-breeding Florida elkhorn coral with samples from Tela.