Game-Changing Cancer Test (test)

An ongoing human study on an experimental cancer test suggests that analyzing blood proteins, instead of tumor DNA, may accurately detect up to 18 early-stage cancers. The US biotech firm, Novelna, presented trial results involving 440 individuals with 18 different cancers, using blood plasma samples from each patient and 44 healthy donors.

The Novelna team achieved high sensitivity and specificity by analyzing trace proteins in the blood. The test, which also considers sex-specific proteins, identified 93% of male and 84% of female cancers at stage I with 99% specificity. The researchers proposed the test as a foundation for a cost-effective, accurate, multi-cancer screening on a population-wide scale, covering major human organs.

Acknowledging the trial’s small size, the team stresses the need for larger trials to confirm accuracy. Despite this, they highlighted the significance of detecting low-level proteins in blood samples for early tumor identification. Implementing such tests could improve survival rates, especially for cancers like breast cancer, and contribute to global efforts in combating the substantial impact of cancer, which currently accounts for one in every six deaths worldwide.

Novelna also anticipates that the test will be much cheaper than current option, with the estimated cost to be below $100.

Related articles: How to Cut Your Risk of Prostate Cancer by a Third and a Saliva Test for Breast Cancer

Not Everything is as Bad as it Seems Part 2

This is the second installment in a series we are writing on how not everything is as bad as it seems. You can check out part one here!

Malthusianism is a theory that states that population growth is potentially exponential while the growth of food supply or other resources is linear. This discrepancy may lead to a Malthusian catastrophe, where population growth surpasses agricultural production, resulting in famine or war and, consequently, poverty and population reduction.

This idea is closely associated with Thomas Robert Malthus, an early 19th century political economist. However, it is still a very popular sentiment held by many. After all, on the surface it seems to make since. We had a population of 1 billion during 1800, now we have over 7 billion. But is this idea actually true?

When viewing the global picture, reconciling Thomas Malthus’ theory with reality presents a challenge. In fact, famine-related deaths have dramatically decreased since the 1800s. This contrast is stark and somewhat counterintuitive given the historical increase in population.

One might initially attribute this trend to advancements in agricultural productivity. Indeed, food availability on a per capita basis has seen a significant rise in recent decades, as evidenced by the increase in food production which has not only kept pace with but exceeded the growth in global population—primarily through enhanced yields per hectare.

Yet, this perspective oversimplifies the issue. A mere lack of food per capita is only one of several factors that can lead to famine deaths. Modern studies on famine suggest that the availability of food is not as critical as one might assume. Instead, these studies point to the pivotal role of public policy and violence. The majority of famines in the 20th and 21st centuries were significantly influenced by conflict, political repression, corruption, or economic mismanagement by authoritarian or colonial rulers.

This observation holds for the most severely food-insecure regions today, including the 2011 famine in Somalia, where food aid was severely limited or misdirected by the militant Islamist group al Shabaab and other groups.

Famine expert Stephen Devereux from the Institute of Development Studies at the University of Sussex encapsulates the evolution of famines across the 20th century, noting that the development of a global capacity to ensure food security coincided with governments’ increased ability to enforce harmful policies.

Consequently, the recent history of famine does not align well with the Malthusian narrative. Against Malthus’ predictions for rapidly growing populations, the per capita food supply has increased across all regions as populations have expanded. Furthermore, famines have become less frequent, not more. In the contemporary world, the presence or absence of famine and the effectiveness of prevention efforts are more significantly influenced by political actions and policy decisions than by mere population dynamics.

This is a very positive development, as it removes one of the big factors in causing famines. While famines are still undoubtedly a problem to be addressed in areas of the world. This steady decline is likely to continue and fears that we will run out of food is, luckily, unfounded.

If you want an in-depth look at how this all works, check out this great article.

Google to Destroy Browsing Data

Google has agreed to eliminate billions of data records as part of a settlement to resolve accusations that it covertly monitored the online activities of individuals who believed they were browsing in private mode.

The settlement terms, submitted on Monday in a federal court in Oakland, California, are awaiting approval from U.S. District Judge Yvonne Gonzalez Rogers.

The settlement is valued between $5 billion and $7.8 billion by the plaintiffs’ attorneys, although it does not include damages for the users, who retain the right to pursue individual claims for damages.

This class action lawsuit, initiated in 2020, represents millions of Google users who have engaged in private browsing since June 1, 2016.

The complaint centered on allegations that Google, through its analytics, cookies, and applications, improperly tracked users who had activated the “Incognito” mode on Google’s Chrome browser or similar privacy settings on other browsers.

As part of the agreement, Google committed to revising its disclosures about data collection in private browsing sessions, an update process it has already started. Additionally, Google will allow users in Incognito mode to block third-party cookies for a duration of five years.

According to the plaintiffs’ legal team, this settlement will result in Google collecting less data from private browsing sessions and consequently earning less revenue from such data.

I’ll do some research and will report back to you once I figure out how and if an individual can make a claim for any damages. I have definitely been using google in “private mode”…

Shock of the Old: 11 Wild ‘Views” of the Future

Promises of improvement are not always as expected, as history shows the unreliability of predicting the future. Attempts to foresee what lies ahead persist, with some visionaries showing remarkable accuracy. Notable examples include Leonardo da Vinci’s predictions of helicopters and fridges, Joseph Glanvill’s 1661 foresight of moon voyages and “magnetic waves” communication, and John Elfreth Watkins’ 1900 predictions of mobile phones and global digital media.

While these visionaries had their hits, they also had misses, such as Watkins’ hopes of eliminating mosquitoes and certain letters, or Arthur Radebaugh’s fanciful uniwheel cars and space monkey colonies. Many predictions merely embellished recent technological developments, showcasing the difficulty in imagining a truly different world.

Fictional depictions often offered wilder visions, with Jules Verne’s 1860 portrayal of Paris in the Twentieth Century including photocopiers and techno music. HG Wells went further, envisioning the atomic bomb. Predictions, whether accurate or not, often reveal more about the hopes and fears of the predictor than the actual future.

These forecasts tend to surge around significant dates and world events, reflecting contemporary preoccupations. The 19th-century’s rapid technological change generated both optimism and anxiety, with recurring themes of societal shifts. The 1960s saw a mix of space-age enthusiasm and Cold War apprehension, exploring alternative scenarios in case of nuclear threats. Reality typically falls between these extremes, and the recurrent predictions of world-ending catastrophes over the past millennium offer a strange comfort – proving that, despite the warnings, we’re still here (for now).

With that, let’s delve into fanciful visions of the past’s imagined futures.

New Sora AI is Shocking

OpenAI’s new text-to-video ai tool, Sora, is absolutely shocking. Text-to-video ai is not brand new, but Sora brings it to a whole new level. (examples down below)

To use Sora, you input a text prompt and Sora generates a video to match your instructions. These videos can be realistic, animated, or any number of combinations you can come up with.

Unlike previous text-to-video ai tools, Sora is capable of creating video clips up to 60 seconds long. In the past, most were very short clips and were generally very fake and unnatural looking.

Sora is not available for public use yet. However, it is expected to become available in the not too distant future.

While it is always a little bit frightening when technology moves at such a fast pace. Many of the main stream ai tools have guardrails in place to stop illegal and exploitative content. This does not always stop bad actors, but thankfully it does help.

What we can all do is promote good and ethical uses of all new technologies.

What Are Some of the Upsides?
There are some very exciting potential uses for this new ai. One of the biggest is for small film, music, and content creators.

Sora can give all of these people the opportunity to create clips or scenes that they would not have the financial means to create otherwise. This could be particularly impactful for people that make content involving Sci-Fi or Fantasy elements. (It is quite difficult to find stock footage of a dragon after all).

It will also give greater ability for people in less fortunate financial situations to be able to realize their artistic visions. This will hopefully make it easier for these people to enter into the film, artistic, and content creation sectors.

It is important to remember that the demo content released was selected by OpenAI for demonstration purposes. We do not know how heavily curated this content was. Once the tool is released to the public we will begin to understand the actual impact it will have.

Below are some of the demos OpenAI released.

If you want to see Sora OpenAI’s full gallery, you can find it on their website here.