Pomegranates Can Help Alzheimer’s Patients

A recent study has found that urolithin A, a natural compound found in pomegranates, may enhance memory and potentially aid in treating Alzheimer’s disease. Researchers at the University of Copenhagen observed significant improvements in memory in mice with Alzheimer’s who were treated with urolithin A.

Alzheimer’s disease manifests through symptoms like forgetfulness, difficulty with words, and confusion about time and place. The study’s findings suggest that urolithin A could mitigate these symptoms and other consequences of dementia, according to Vilhelm Bohr, Affiliate Professor at the University’s Department of Cellular and Molecular Medicine.

While the study was conducted on mice, the results are promising enough to warrant upcoming human clinical trials. Previous research from the same team highlighted the role of nicotinamide riboside in facilitating the removal of damaged mitochondria from the brain, a process crucial for addressing neurodegenerative diseases like Alzheimer’s and Parkinson’s.

Bohr explained that many patients with these conditions experience mitochondrial dysfunction, hindering the brain’s ability to clear out weak mitochondria. Stimulating this clearance process, known as mitophagy, has shown positive effects on brain function. Interestingly, urolithin A appears to stimulate mitophagy similarly to nicotinamide riboside supplements, potentially offering therapeutic benefits.

Despite these promising findings, researchers are still determining the optimal dosage of urolithin A for humans. Bohr emphasized the need for further investigation but expressed optimism that urolithin A could be used preventively with minimal side effects, as observed in previous studies on related compounds.

The study, titled “Urolithin A improves Alzheimer’s disease cognition and restores mitophagy and lysosomal functions,” has been published in Alzheimer’s and Dementia.

AI Finds Elephants Use Names

Researchers from Colorado State University, Save the Elephants, and ElephantVoices used machine learning to study how elephants communicate. They found that elephants use unique calls akin to names to address specific individuals within their herds, rather than addressing the entire group uniformly.

This discovery sheds light on the sophisticated social dynamics and communication abilities of elephants, crucial for managing human-elephant conflicts in shared landscapes. By analyzing recorded calls, the team observed that elephants responded more distinctly to calls directed at them personally, highlighting the personalized nature of these vocalizations.

George Wittemyer, a study co-author, emphasizes that such naming practices in animals reflect complex communication systems essential for navigating social interactions, paralleling human evolutionary pressures.

WATCH a video explainer below…

Washington State Bans Single-Use Foam

In 2021, Washington state passed a law banning single-use polystyrene food and drink containers, which has now taken effect.

Polystyrene, made from fragile hollow beads of various plastics, is considered one of the most environmentally harmful plastics. Despite its lightweight, durable, and insulating properties, it remains in use for packaging and other applications. Polystyrene can take over 1,000 years to decompose, releasing microplastics into soil and water throughout that time.

According to Oceana, at least 11 states have enacted laws to phase out expanded polystyrene foam. The environmental group advocates for nationwide bans on the material. Seattle prohibited foam food containers approximately 15 years ago, and Oregon Governor Tina Kotek signed a similar law last year.

Although recycling polystyrene is possible, Washington’s Department of Ecology notes it is costly and most residential recycling programs do not accept it. Food residue complicates recycling further, which is why the ban targets takeaway containers. Polystyrene can also blow around and contaminate other materials during transport and at recycling facilities.

Violators of the ban will face fines but also receive support and resources to help them find alternative container options. Possible replacements include aluminum containers, which are reusable and provide better insulation for food.

‘Extinct’ Stork Spotted in UK After 600 Years

A white stork was recently spotted flying over Cheshire, England, marking an event not seen for generations. These birds have been extinct in England for 600 years, dating back to the time of Martin Luther’s reforms. However, they have been reintroduced and breeding in the country for several years due to conservation efforts.

The White Stork Project in southern England, supported by birds donated from the Warsaw Zoo, has played a key role in this reintroduction. The zoo’s storks had been rescued from accidents involving roads or powerlines.

Some of these storks are kept at the Cotswold Wildlife Park, and each year, their offspring are moved to the Knepp Estate and Wadhurst Park in Sussex. Here, they grow up in a natural environment, learning the skills needed to survive in the English countryside.

Cheshire is quite far from the Cotswolds and the Knepp Estate, where the reintroduction efforts are centered. “There are no plans to reintroduce them here in Cheshire, but it was great to see one this far north,” Banks added.

Despite their long absence in England, the white stork is classified as a species of least concern and can be found in regions such as Kenya, Palestine, Turkey, and Kazakhstan.

You can watch a live nest camera of a stork family at the Knepp Estate, courtesy of the White Stork Project, where juveniles can be seen competing for food brought by their parents.

World’s Largest Genome Discovered

On New Caledonia, a species of fern has been discovered with the longest genome (is the entire set of DNA instructions found in a cell.)of any known living organism.

Its genome is 50 times longer than a human’s, 7% longer than the previous record-holder, and 20% longer than the animal with the longest genome. While humans have 23 pairs of chromosomes, this fern has 416. If unraveled, its DNA would stretch higher than Big Ben in London.

Dr. Ilia Leitch from the Royal Botanical Gardens, Kew, remarked on the significance of this discovery, highlighting the diverse nature of plant DNA and its implications for understanding global biodiversity. She also noted the potential to explore the biological limits of genome size.

Twenty-thousand species have had their genomes sequenced and through that we learned that having a large genome isn’t always beneficial. Larger genomes demand more resources for replication, repair, and transcription, and require a larger cell nucleus.

Dr. Leitch explained to Reuters that species with larger genomes are more prone to extinction, similar to how simpler machines tend to be more durable than complex ones.

Previously, the longest genome was held by the Japanese flowering plant Paris japonica, while the African marbled lungfish (Protopterus aethiopicus) has the longest animal genome. The smallest genome belongs to the fungus Encephalitozoon intestinalis, with 2.6 megabase pairs. In comparison, the New Caledonian fern has 168 gigabase pairs, akin to comparing the file size of Tetris to a modern game like The Witcher.